Modified Low Ratio Ketogenic Therapy in the Treatment of Adults with Super Refractory Status Epilepticus

Identification: JPEN2211
Credits (Post Test and/or Evaluation Required)
Available until 11/30/2023
  • 1.00 - Dietitian
  • 1.00 - Nurse
  • 1.00 - Pharmacist
  • 1.00 - Physician
  • 1.00 - Other


Activity Instructions: Read the full article and take the exam by clicking the "CE Information" tab.

CE Credit: CE credit available for dietitians, nurses, pharmacists and physicians

Total Credit Hours: 1.0

Release Date: November 1, 2022

Expiration Date (all CE credit must be claimed by the expiration date): November 30, 2023

Issue: 8

Volume: 46

Journal: Journal of Parenteral and Enteral Nutrition (JPEN)

Author (s):

Neha Kaul, BNutrDiet, APD, Senior Dietitian – Grade 4, Epilepsy and Neurology, Department of Nutrition and Dietetics, Alfred Hospital, Melbourne, Victoria; Research Associate, Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia

Judy Nation, MND, Specialist Dietitian, Medical Science Platform Lead Inborn Errors of Metabolism and Ketogenic Diets, Vitaflo Australia, Strathmore, Victoria, Australia

Joshua Laing, MBBS, FRACP, Neurologist and Epileptologist; Clinical Research Fellow, Departments of Neurosciences and Neurology, Alfred Hospital and Monash University, Melbourne, Victoria, Australia

John-Paul Nicolo. PhD, Head of Epilepsy Service, Melbourne Health; Consultant Neurologist, Melbourne Health and Alfred Health; Adjunct Research Associate, Central Clinical School, Monash University, Parkville, Victoria, Australia

Adam M. Deane, MBBS, PhD, FCICM, FRACP, Deputy Head, Department of Critical Care; Principal Research Fell (Level D), University of Melbourne; Head of Research, Intensive Care Unit; Deputy Director, Intensive Care Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia

Andrew A. Udy, BHB, MBChB, PGCert(AME), PhD, FCICM, Professor of Research – Critical Care; Department of Intensive Care and Hyperbaric Medicine, The Alfred Hospital School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia

Patrick Kwan, BMedSci(hons), MB BChir, PhD, FRCP, FRACP, FAHMS, Co-director, Monash Institute of Medical Engineering, Monash University, Melbourne; Professor of Neurology, Department of Neuroscience, Monash University, Melbourne, Victoria, Australia

Terence J. O'Brien, MB BS, MD, FRACP, FRCPE, FAHMS, FAES, Chair of Medicine (Neurology) and Head, Central Clinical School, Monash University, Melbourne; Director, Alfred Brain and Deputy Director of Research, Alfred Hospital, Melbourne, Victoria, Australia

Link to article: 

Journal-based CE Activity Overall Goal:
The JPEN Editor, in concurrence with ASPEN’s Education and Professional Development Committee, selected this article to be offered for CE credit to fill an observed learning need in the arena of clinical nutrition and metabolism. This CE activity serves to promote the process of life-long learning for physicians, dietitians, pharmacists, and nurses by providing peer-reviewed journal articles that fully qualify for continuing education credits.

Goal and Target Audience:
This educational activity is directed toward clinical nutrition and metabolism professionals and others who wish to update their knowledge of clinical nutrition and metabolism. By participating in this educational activity, the reader may expect to:

  • Acquire knowledge in the area of clinical nutrition and metabolism research.
  • Update or confirm your understanding of appropriate clinical nutrition and metabolism practices.
  • Identify further learning needs as they relate to the subject matter.

Learning Objectives:

  1. Identify patients who should be considered for ketogenic therapy for super refractory status epilepticus
  2. Formulate a ketogenic nutrition prescription for an adult requiring ketogenic therapy for super refractory status epilepticus
  3. Identify the key parameters for monitoring of ketogenic therapy in the ICU

Requirements for Successful Completion:

To obtain CE credit for this activity, attendees must read the journal article in its entirety, complete an online assessment for each article and achieve a score of 100%, and complete an online activity evaluation. All are located in ASPEN’s eLearning Center ( All CE credit must be claimed prior to the expiration date, no exceptions. Pharmacists must provide their birthday (MMDD) and NABP e-PID. Details are available at

Accreditation Statement

custom image

In support of improving patient care, the American Society for Parenteral and Enteral Nutrition (ASPEN) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

ASPEN designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credits TM per article. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Pharmacists: ASPEN designates this activity for a maximum of 1.0 contact hours/0.1 CEUs. ACPE UAN: JA0002345-0000-22-122-H04-P. Knowledge Activity.

Nurses: ASPEN designates this activity for a maximum of 1.0 nursing contact hours. ASPEN is approved as a provider of continuing nursing education by the California Board of Nursing, provider number CEP3970.

Dietitians: ASPEN designates this activity for a maximum of 1.0 CPEUs

custom image

custom image

This activity was planned by and for the healthcare team, and learners will receive 1 Interprofessional Continuing Education (IPCE) credit for learning and change.

Policies and Information:

Non-Commercialism: ASPEN subscribes to the Standards for Integrity and Independence in Accredited Continuing Education. ASPEN does not provide programs that constitute advertisement or include promotional materials. ASPEN does not endorse any products.

Computer Requirements and Technical Support. Computer with internet connection to access the online assessment and evaluation for each journal article. If the journal article is read electronically, then the ability to read a PDF document is necessary. Users should enable pop-ups if attempting to read articles electronically. 

For technical difficulties, please contact Broadcastmed Customer Support:

by phone: 1.860.953.2900
Phone support is available 8am-8pm EST Monday through Friday.
by email:

Privacy and Confidentiality. ASPEN respects the privacy of its members and customers. Companies that receive personal information from ASPEN to execute the business of ASPEN may use information only for that purpose.

Refund Policy. Refunds are not available.

Grievances. Grievances must be submitted in writing to Director of Education and Research at ASPEN, 8401 Colesville Road, Ste 510, Silver Spring, MD 20910.

Commercial Support and Sponsorship:

No commercial support has been received for this CE activity.

Commercial Relationships Disclosures and Conflicts of Interest (COI) of Authors and Editor-in-Chief and Associate Editors:

The following individuals have no financial relationships with ineligible companies: Neha Kaul, John-Paul Nicolo, Joshua Laing 

Judy Nation, Vitaflo Australia, employee, not involved in study design or implementation.

Adam Deane: Baxter Healthcare and Gilead Sciences, lecture fees

Andrew Udy, in-kind support (trial consumables) from Integra Lifesciences

Patrick Kwan, UCB Pharma, consultant; Eisai, consultant and speaker; Angelini Pharma, speaker

Terence O'Brien: consultant and research grants - Eisai, UCB, Kinosis Therapeutics, ES Therapeutics, Biogen 

Among the JPEN Associate Editors, Lingtak-Neander Chan, Jean-Charles Preiser, Vanessa Garcia-Larsen, Jamie Robertson, Djøra Soeteman have no financial relationships with ineligible companies.

Manpreet Mundi: Fresenius Kabi, research grant; Nestle, research grant; Realfood Blends, research grant; Vectiv Bio, research grant; Baxter, advisory board; Zealand, emerging expert group.

Marion Winkler: Takeda, member of Gattex SBS Multidisciplinary Care Team Advisory Board.

JPEN EIC, Kenneth Christopher has no financial relationships with ineligible companies.

ASPEN staff have no financial relationships with ineligible companies.

All relevant financial relationships have been mitigated via the journal peer review process.

Note: an ineligible company is one whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. For specific examples of ineligible companies visit

Financial relationships are relevant if the following three conditions are met for the prospective person who will control content of the education:

  • A financial relationship, in any amount, exists between the person in control of content and an ineligible company.
  • The financial relationship existed during the past 24 months.
  • The content of the education is related to the products of an ineligible company with whom the person has a financial relationship.



Credits: None available.