Association between prealbumin, all-cause mortality, and response to nutritional treatment in patients at nutritional risk: Secondary analysis of a randomized-controlled trial

Identification: JPEN2305
Credits (Post Test and/or Evaluation Required)
Available until 05/31/2024
  • 1.00 - Dietitian
  • 1.00 - Nurse
  • 1.00 - Pharmacist
  • 1.00 - Physician
  • 1.00 - Other

Activity Instructions: Read the full article and take the exam by clicking the "CE Information" tab.

CE Credit: CE credit available for dietitians, nurses, pharmacists and physicians

Total Credit Hours: 1.0

Release Date: May 1, 2023

Expiration Date (all CE credit must be claimed by the expiration date): May 31, 2024

Issue: 4

Volume: 47

Journal: Journal of Parenteral and Enteral Nutrition (JPEN)

Author (s):

Céline Bretscher MD, Medical Resident, Medical University Department, Division of General Internal and Emergency Medicine, Kantonsspital Aarau, Aarau, Switzerland

Michelle Buergin Bsc, Research Associate, Cantonal Hospital St.Gallen, Clinic for Psychosomatics & Psychiatry; Medical University Department, Division of General Internal and Emergency Medicine, Kantonsspital Aarau, Aarau, Switzerland

Gianna Gurzeler Bsc, Medical Student, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland

Nina Kägi-Braun MD, Medical Resident, Endocrinology, Diabetes, and Metabolism, University Clinic of Medicine, Cantonal Hospital Aarau, Aarau, Switzerland; Consultant physician Spital Zofingen, Aarau, Switzerland

Carla Gressies MSc, Clinical Research Associate and PhD Student, Medical University Department, Division of General Internal and Emergency Medicine, Kantonsspital Aarau, Aarau, Switzerland

Pascal Tribolet MSc, PhD Student, Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences, Department of Health Professions, Bern University of Applied Sciences, Bern, Switzerland

Dileep N. Lobo MD, Professor of Gastrointestinal Surgery, Gastrointestinal Surgery, Nottingham Digestive Diseases Centre, National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Queen's Medical Centre, Nottingham, UK

David C. Evans MD, Trauma and Critical Care Surgeon, Ohio Health Grant Medical Center and Ohio Health Mansfield Hospital; Adjunct Clinical Professor of Surgery, Ohio University; Medical Director, Ohio Health System Nutrition Support Team, Columbus OH

Zeno Stanga MD, Associate Professor for Internal and Nutritional Medicine, Division of Diabetology, Endocrinology, Nutritional Medicine, and Metabolism, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

Beat Mueller MD, Physician, Medical University Department, Division of General Internal and Emergency Medicine, Kantonsspital Aarau, Aarau, Switzerland

Philipp Schuetz MD, Head, Department of General Internal Medicine and Emergency Medicine, Kantonsspital Aarau, Aarau, Switzerland

Link to article:

Journal-based CE Activity Overall Goal:
The JPEN Editor, in concurrence with ASPEN’s Education and Professional Development Committee, selected this article to be offered for CE credit to fill an observed learning need in the arena of clinical nutrition and metabolism. This CE activity serves to promote the process of life-long learning for physicians, dietitians, pharmacists, and nurses by providing peer-reviewed journal articles that fully qualify for continuing education credits.

Goal and Target Audience:
This educational activity is directed toward clinical nutrition and metabolism professionals and others who wish to update their knowledge of clinical nutrition and metabolism. By participating in this educational activity, the reader may expect to:

  • Acquire knowledge in the area of clinical nutrition and metabolism research.
  • Update or confirm your understanding of appropriate clinical nutrition and metabolism practices.
  • Identify further learning needs as they relate to the subject matter.

Learning Objectives:

  1. Summarize the physio-pathological mechanism of prealbumin and its metabolism
  2. Describe the clinical use of prealbumin and other visceral proteins in the management of patients with malnutrition
  3. Utilize nutritional biomarkers in management of malnutrition

Requirements for Successful Completion:

To obtain CE credit for this activity, attendees must read the journal article in its entirety, complete an online assessment for each article and achieve a score of 100%, and complete an online activity evaluation. All are located in ASPEN’s eLearning Center ( All CE credit must be claimed prior to the expiration date, no exceptions. Pharmacists must provide their birthday (MMDD) and NABP e-PID. Details are available at

Accreditation Statement

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In support of improving patient care, the American Society for Parenteral and Enteral Nutrition (ASPEN) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

ASPEN designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credits TM per article. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Pharmacists: ASPEN designates this activity for a maximum of 1.0 contact hours/0.1 CEUs. ACPE UAN: JA0002345-0000-23-035-H99-P. Knowledge Activity.

Nurses: ASPEN designates this activity for a maximum of 1.0 nursing contact hours. ASPEN is approved as a provider of continuing nursing education by the California Board of Nursing, provider number CEP3970.

Dietitians: ASPEN designates this activity for a maximum of 1.0 CPEUs

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This activity was planned by and for the healthcare team, and learners will receive 1 Interprofessional Continuing Education (IPCE) credit for learning and change.

Policies and Information:

Non-Commercialism: ASPEN subscribes to the Standards for Integrity and Independence in Accredited Continuing Education. ASPEN does not provide programs that constitute advertisement or include promotional materials. ASPEN does not endorse any products.

Computer Requirements and Technical Support: Participants will need a computer with internet connection to access the online assessment and evaluation for each journal article. If the journal article is read electronically, then the ability to read a PDF document is also necessary. Users should enable pop-ups if attempting to read article electronically. 

For technical difficulties, please contact Broadcastmed Customer Support:

by phone: 1.860.953.2900
Phone support is available 8am-8pm EST Monday through Friday.
by email:

Privacy and Confidentiality: ASPEN respects the privacy of its members and website visitors. Companies that receive personal information from ASPEN in order to execute the business of ASPEN may use personal information only for that purpose.

Refund Policy: Refunds are not available.

Grievances: Grievances must be submitted in writing to Director of Education at ASPEN 8401 Colesville Road, Ste 510, Silver Spring, MD 20910

Commercial Support and Sponsorship:

No commercial support or sponsorship has been received for this continuing education activity.

Commercial Relationships Disclosures and Conflicts of Interest (COI) of Authors and Editor-in-Chief and Associate Editors

The following individuals have no financial relationships with ineligible companies: Beat Mueller, Céline Bretscher, Michelle Buergin, Carla Gressies, Gianna Gurzeler, Nina Kägi-Braun, Zeno Stanga, Pascal Tribolet

Among the JPEN Associate Editors, Jean-Charles Preiser, Vanessa Garcia-Larsen, Jamie Robertson, Russell de Souza, Simone CM Silvestre, Djøra Soeteman have no financial relationships with ineligible companies.

JPEN EIC, Kenneth Christopher has no financial relationships with ineligible companies.

ASPEN staff have no financial relationships with ineligible companies.

David C. Evans: Abbott Nutrition, consultant, speaker; Coram, advisory board, speaker (not ineligible company); Fresenius Kabi, consultant, speaker; Alcresta, consultant, speaker

Dileep N. Lobo: BBraun, educational grant, ended; Abbott, speaker, ended; Nestle, speaker, ended; Corza, speaker, ended

Philipp Schuetz: Research support from Nestle, Abbott, Thermo, bioMerieux, and Roche

Marion Winkler: VectivBio, independent consultant

Manpreet Mundi: Fresenius Kabi, research grant; Nestle, research grant; Rockfield, research grant; VectivBio, research grant; NorthSea, advisory board.

Isabel Correia: Abbott, speaker; Nestle speaker, relationship ended; Danone speaker, relationship ended; Fresenius, consulting; Baxter, speaker, relationship ended

Annika Reintam Blaser: Nutricia Danone, speaker, relationship ended; VIPUN Medical, consultant, relationship ended

Olav Rooyackers: Nutricia, advisory meeting, speaker, relationship ended; Fresenius Kabi, research grant, consultant, speaker/teacher; Baxter, speaker/teacher, relationship ended; Nestle, speaker/teacher, relationship ended

All relevant financial relationships have been mitigated via the journal peer review process.

Note: an ineligible company is one whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. For specific examples of ineligible companies visit

Financial relationships are relevant if the following three conditions are met for the prospective person who will control content of the education:

  • A financial relationship, in any amount, exists between the person in control of content and an ineligible company.
  • The financial relationship existed during the past 24 months.
  • The content of the education is related to the products of an ineligible company with whom the person has a financial relationship.


  • 1.00 - Dietitian
  • 1.00 - Nurse
  • 1.00 - Pharmacist
  • 1.00 - Physician
  • 1.00 - Other