Cost-utility analysis of 4% tetrasodium ethylenediaminetetraacetic acid, taurolidine and heparin lock to prevent central line-associated blood-stream infections in children with intestinal failure

Identification: JPEN2401
Credits (Post Test and/or Evaluation Required)
Available until 12/31/2024
  • 1.00 - Dietitian
  • 1.00 - Nurse
  • 1.00 - Pharmacist
  • 1.00 - Physician
  • 1.00 - Other

Activity Instructions: Read the full article and take the exam by clicking the "CE Information" tab.

CE Credit:
CE credit available for dietitians, nurses, pharmacists and physicians

Total Credit Hours: 1.0

Release Date: January 1, 2024

Expiration Date (all CE credit must be claimed by the expiration date): December 31, 2024

Issue: 1

Volume: 48

Journal: Journal of Parenteral and Enteral Nutrition (JPEN)

Author (s):

Daniela Gattini, MD, Assistant Professor – Academic Clinician, Division of Gastroenterology Hepatology & Nutrition, Department of Pediatrics, Faculty of Medicine, University of Toronto. Toronto, ON, Canada

Han Yan, MD, Candidate for the College of Family Physicians of Canada, Department of Family and Community Medicine, University of Toronto, Toronto, ON Canada

Christina Belza, MN, PhD, Post-Doctoral Fellow, Edwin S.H. Leong Centre for Healthy Children, The Hospital for Sick Children, Toronto, ON, Canada

Yaron Avitzur, MD, Staff Gastroenterologist, Clinician-Academic, Division of Gastroenterology Hepatology & Nutrition, Department of Pediatrics, Faculty of Medicine, University of Toronto. Toronto, ON, Canada

Paul Wales, BSc, MD, MSc, FRCSC, FACS, FASPEN, Professor of Surgery, Faculty of Medicine, University of Cincinnati; Surgical Director, Intestinal Rehabilitation Program, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

Link to article:

Journal-based CE Activity Overall Goal:
The JPEN Editor, in concurrence with ASPEN’s Education and Professional Development Committee, selected this article to be offered for CE credit to fill an observed learning need in the arena of clinical nutrition and metabolism. This CE activity serves to promote the process of life-long learning for physicians, dietitians, pharmacists, and nurses by providing peer-reviewed journal articles that fully qualify for continuing education credits.

Goal and Target Audience:
This educational activity is directed toward clinical nutrition and metabolism professionals and others who wish to update their knowledge of clinical nutrition and metabolism. By participating in this educational activity, the reader may expect to:

  • Acquire knowledge in the area of clinical nutrition and metabolism research.
  • Update or confirm your understanding of appropriate clinical nutrition and metabolism practices.
  • Identify further learning needs as they relate to the subject matter.

Learning Objectives:

  1. Identify catheter lock solutions used in patients with intestinal failure that have antimicrobial properties.
  2. Describe the relevance of health economic evaluations assessing different catheter lock solutions in pediatric intestinal failure.
  3. Define basic concepts of health economic evaluations.
  4. Apply cost-utility analysis results to clinical practice.
  5. Determine how health economic evaluations can guide areas of future research in the field.

Requirements for Successful Completion:

To obtain CE credit for this activity, attendees must read the journal article in its entirety, complete an online assessment for each article and achieve a score of 100%, and complete an online activity evaluation. All are located in ASPEN’s eLearning Center ( All CE credit must be claimed prior to the expiration date, no exceptions. 

ASPEN submits data as required to the CPE Monitor for pharmacists. ASPEN submits physician earned CME credit into Pars. ASPEN does not submit data to any other credentialing organization.

Pharmacists and physicians, please note that ASPEN will upload earned CE credit into the appropriate system within the required timeframe. Any credit not claimed by the deadline will not be entered. Please provide your correct information when completing your evaluation and claiming CE credit. ASPEN submits only the information that is entered by the pharmacist or physician when credit is claimed and is not responsible for following up to obtain any corrected information to ensure an error-free submission.

Accreditation Statement

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In support of improving patient care, the American Society for Parenteral and Enteral Nutrition (ASPEN) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

ASPEN designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credits TM per article. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Pharmacists: ASPEN designates this activity for a maximum of 1.0 contact hours/0.1 CEUs. ACPE UAN: JA0002345-0000-24-084-H01-P. Knowledge Activity.

Nurses: ASPEN designates this activity for a maximum of 1.0 nursing contact hours. ASPEN is approved as a provider of continuing nursing education by the California Board of Nursing, provider number CEP3970.

Dietitians: ASPEN designates this activity for a maximum of 1.0 CPEUs

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This activity was planned by and for the healthcare team, and learners will receive 1 Interprofessional Continuing Education (IPCE) credit for learning and change.

Policies and Information:

Non-Commercialism: ASPEN subscribes to the Standards for Integrity and Independence in Accredited Continuing Education. ASPEN does not provide programs that constitute advertisement or include promotional materials. ASPEN does not endorse any products.

Computer Requirements and Technical Support: Participants will need a computer with internet connection to access the online assessment and evaluation for each journal article. If the journal article is read electronically, then the ability to read a PDF document is also necessary. Users should enable pop-ups if attempting to read article electronically. 

For technical difficulties, please contact Broadcastmed Customer Support:

by phone: 1.860.953.2900
Phone support is available 8am-8pm EST Monday through Friday.
by email:

Privacy and Confidentiality: ASPEN respects the privacy of its members and website visitors. Companies that receive personal information from ASPEN in order to execute the business of ASPEN may use personal information only for that purpose.

Refund Policy: Refunds are not available.

Grievances: Grievances must be submitted in writing to Director of Education at ASPEN 8401 Colesville Road, Ste 510, Silver Spring, MD 20910

Commercial Support and Sponsorship:

No commercial support or sponsorship has been received for this continuing education activity.

Commercial Relationships Disclosures and Conflicts of Interest (COI) of Authors and Editor-in-Chief and Associate Editors

The following individuals have no financial relationships with ineligible companies: Christina Belza, Daniela Gattini, Han Yan

Among the JPEN Associate Editors, Jean-Charles Preiser, Vanessa Garcia-Larsen, Jamie Robertson, Russell de Souza, Simone CM Silvestre, Djøra Soeteman have no financial relationships with ineligible companies.

JPEN EIC, Kenneth Christopher has no financial relationships with ineligible companies.

ASPEN staff have no financial relationships with ineligible companies.

Yaron Avitzur: Takeda Pharmaceuticals, consultant and grant; SterilCare Inc., supported a conference; Zealand Pharma, supported a conference.

Paul Wales: Takeda Pharmaceuticals, advisory board, research support; SterilCare Inc., in kind product for publication; Baxter, research support

Marion Winkler: VectivBio, independent consultant

Manpreet Mundi: Fresenius Kabi, research grant; Nestle, research grant; Rockfield, research grant; VectivBio, research grant; NorthSea, advisory board.

Annika Reintam Blaser: Nutricia Danone, speaker, relationship ended; VIPUN Medical, consultant, relationship ended

Olav Rooyackers: Nutricia, advisory meeting, speaker, relationship ended; Fresenius Kabi, research grant, consultant, speaker/teacher; Baxter, speaker/teacher, relationship ended; Nestle, speaker/teacher, ended

All relevant financial relationships have been mitigated via the journal peer review process.

Note: an ineligible company is one whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. For specific examples of ineligible companies visit

Financial relationships are relevant if the following three conditions are met for the prospective person who will control content of the education:

  • A financial relationship, in any amount, exists between the person in control of content and an ineligible company.
  • The financial relationship existed during the past 24 months.
  • The content of the education is related to the products of an ineligible company with whom the person has a financial relationship.


  • 1.00 - Dietitian
  • 1.00 - Nurse
  • 1.00 - Pharmacist
  • 1.00 - Physician
  • 1.00 - Other