Lipid injectable emulsions (ILEs) are a dense source of calories and are a source of the essential fatty acids (EFAs), important for cell membrane development and precursors to key modulators involved in cellular pathways of the immune response. In the early 1970s, the ILE approved for use in the United States was a solely soybean oil-based fat emulsion (SOFE) and until recently was the only FDA approved product available in the US market. While very little has changed in the provision of ILEs over the last four decades in the United States, multiple products have come to market in other areas of the world such as Latin America, each with the intent of being an ideal oil source. With the recent approval of newer ILEs in the US market, opportunities for expanded use of alternative lipid sources have been possible. This webinar will include a discussion of the use of recently FDA approved ILE products, particularly the mixed-oil based fat emulsion (MOFE) with practical tips from those with experience using the products.

Learning Objectives:

• Compare and contrast the various lipid injectable emulsions currently available
• Describe the benefits and challenges in using the newer lipid injectable emulsions
• Determine the appropriate use of newer alternative lipid injectable emulsions in neonatal, pediatric, and adult populations