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ASPEN 2019 Nutrition Science & Practice Conference


RW-2019 - Research Workshop: The Relationship Between the Intestinal Barrier and Chronic Disease


Mar 23, 2019 7:30am ‐ Mar 23, 2019 4:00pm


Credits: None available.

Description

In the U.S., 86% of the nation’s $2.7 trillion annual health care expenditures are for individuals with chronic and mental health conditions. A growing body of evidence indicates that a compromised intestinal epithelial barrier influences the incidence and severity of chronic diseases, such as type 1 and 2 diabetes and obesity, primary intestinal disorders such as celiac disease and inflammatory bowel disease, and neurologic disorders such as autism and Parkinson’s disease. Despite growing evidence linking diet, environment, the intestinal epithelium, and inflammatory diseases, there is a gap between the science and healthcare policy and practice. This large gap presents an enormous opportunity to develop scientifically based strategies, healthcare policies and clinical guidelines to prevent and reduce the risk of chronic inflammatory diseases with the aim of developing interventions that promote an intact and healthy intestinal epithelium. To this end, it is crucial that health care providers understand how nutrition, environment, microbiota, and intestinal epithelium interact. This workshop addresses an important and evolving field of research with potential for clinical impact that you will not want to miss.

Learning Objectives:

  • Describe the properties and functions of the intestinal epithelial barrier
  • Describe how the microbiota and nutrition modulate the intestinal epithelial barrier
  • Summarize how the intestinal epithelial barrier impacts risk for various chronic inflammatory diseases
  • Evaluate the current literature on factors that influence intestinal epithelial barrier integrity
  • Explore opportunities for translational science from communication and collaboration among interdisciplinary researchers and clinicians that can bring about changes in health care practice and public policy relevant to the management and prevention of inflammatory-based chronic diseases

Moderators:  Yimin Chen, PhD, RD, CNSC; Enid Martinez, MD

Speaker(s):

  • Yimin Chen, PhD, RD, CNSC, Assistant Professor, Margaret Ritchie School of Family & Consumer Sciences, University of Idaho, Moscow, ID
  • Enid E. Martinez, MD, Associate in Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital; Assistant Professor of Anaesthesia, Harvard Medical School, Boston, MA
  • Jerrold Turner, MD, PhD, Professor, Pathology, Harvard Medical School; Professor, Medicine, Brigham and Women's Hospital, Boston, MA
  • Gary D. Wu, MD, Professor of Medicine; Co-Director, PennCHOP Microbiome Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
  • Kelly Tappenden, PhD, RD, FASPEN, Professor and Head, Department of Kinesiology and Nutrition, University of Illinois at Chicago; Editor-in-Chief, Journal of Parenteral and Enteral Nutrition, Chicago, IL
  • Daniel Winer, MD, Anatomical Pathologist, University Health Network; Scientist, Toronto General Research Institute; Assistant Professor, Department of Laboratory Medicine and Pathobiology, Department of Immunology,University of Toronto, Toronto, Ontario, Canada
  • Alessio Fasano, MD, Professor of Pediatrics, Harvard Medical School; W. Allan Walker Chair of Pediatric Gastroenterology and Nutrition; Division Chief, Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Boston, MA
  • Brittany Needham, PhD, Postdoctoral Scholar, Department of Biology and Biological Engineering, California Institute of Technology – Sarkis Mazmanian Lab, Pasadena, CA
  • Amir Zarrinpar, MD, PhD, Assistant Professor, Division of Gastroenterology, University of California San Diego, La Jolla, CA

Credits

Credits: None available.

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