Description
This one-day research workshop will provide key knowledge and a conceptual framework with which to understand and study the metabolic basis of cancer nutrition therapy. Unlike simple malnutrition, cancer patients’ negative energy balance and profound skeletal muscle wasting is driven by a combination of reduced food intake and abnormal metabolism (ie, elevated energy expenditure, insulin resistance, lipolysis, and proteolysis), which aggravate weight loss and are provoked by systemic inflammation and catabolic factors. These metabolic changes explain why cancer-associated malnutrition cannot be fully reversed by conventional nutrition support. The goal of this workshop is to provide new findings on the specific nature of the metabolic changes that underlie malignant disease, and details of specific nutrition therapies that may reverse abnormal metabolism, permit robust anabolic responses, and improve cancer treatment outcomes.
Objectives:
- Outline key concepts in cancer-related malnutrition
- Integrate new knowledge on human metabolism in the tumor-bearing state toward applications in cancer nutrition therapy
- Understand specific limitations to successful nutrition therapy in cancer patients
- Identify potential future research directions in this arena
Speaker(s):
- Vickie
Baracos,
PhD,
Professor,
Department of Oncology, Division of Palliative Care Medicine, University of Alberta, Edmonton, Alberta, Canada
Speaker(s):
- Philip
Atherton,
PhD, AFHEA,
Associate Professor,
University of Nottingham,Derby, United Kingdom
- Stephanie
Chevalier,
PhD,
Assistant Professor, Department of Medicine,
McGill University
- Jim
Dalton,
PhD,
Vice President, CSO,
GTx, Inc.
- Vera
Mazurak,
PhD,
Associate Professor, Human Nutrition, Department of Agricultural, Food and Nutritional Science,
University of Alberta
- Carl
M. Prado,
PhD, RD,
Director, Human Nutrition Research Unit; Associate Professor & Campus Alberta Innovates Program (CAIP) Chair in Nutrition, Food and Health,
Department of Agricultural, Food and Nutritional Science, Division of Human Nutrition, University of Alberta, Edmonton, Alberta, Canada
- Blake
Rasmussen,
PhD,
Lloyd and Sue Ann Hill Professor of Healthy Aging, Interim Chair, Department of Nutrition and Metabolism,
University of Texas Medical Branch
