Objectives:

Describe normal physiology of the pancreas and consequences of exocrine pancreatic enzyme deficiency on digestion, including differences between pediatric and adult patients
List several causes of exocrine pancreatic insufficiency in different age groups from infants to geriatric patients
Discuss the indications, contraindications, and complications of pancreatic enzyme replacement therapy (PERT)
Explain factors affecting dose and product selection for PERT, and appropriate administration precautions during altered nutrient intake and feeding routes (oral, gastric tube, jejunal tube)

Molly Bozic MD

Riley Hospital for Children at IU Health, Indianapolis, IN