Leo Buckley PharmD, MPH
Assistant Professor, Division of Cardiology, Department of Internal Medicine, UT Southwestern Medical Center; Assistant Professor, Department of Epidemiology, UT Southwestern Peter O’Donnell Jr. School of Public Health, Dallas, TX
Leo F. Buckley, PharmD, MPH, is an Assistant Professor of Medicine and Epidemiology in the Departments of Internal Medicine and Epidemiology at UT Southwestern Medical Center and a Core Faculty Member of the Translational Cardiovascular Epidemiology Research Unit. He provides evidence-based pharmacotherapy for patients with complex cardiomyopathies in the Cardiomyopathy and Heart Failure Clinic. His clinical research program integrates mechanistic clinical trials, epidemiology, and advanced multi-omics (pharmaco-genomics/-proteomics/-metabolomics and single-cell analysis) to define how drugs modulate cardiac structure and function with the overall goal of developing novel, precision therapeutics for the prevention and treatment of heart failure. Current areas of emphasis include: defining the effects of iron repletion on cardiac structure, function, and energetics; elucidating molecular mechanisms of colchicine and anti-cytokine therapies; applying genomic, proteomic, metabolomic and single-cell analysis data to optimize cardiovascular drug interventions.