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TH21 - Key Clinical Trials: Where Do We Go Next? (TH21)

‐ Apr 20, 2023 4:00pm


  1. Discuss the rationale for the EFFORT trial
  2. Summarize the results of the EFFORT trial
  3. Cogitate on translational strategies to optimize signals in future critical care nutrition trials
  4. Describe efficacy and safety of glepaglutide
  5. Discuss the future clinical and research implications of the findings of EASE SBS-1 


Putting in the EFFORT: The Basis for Protein in Critically Ill Patients 
Jayshil Patel, MD, Associate Professor of Medicine, Division of Pulmonary and Critical Care Medicine, Medical College of Wisconsin, Milwaukee, WI

It Was Worth the EFFORT: Results of the Largest Protein Dose Trial in Critically Ill Patients 
Christian Stoppe, FAHA, FESC, Professor of Medicine, Department of Anesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Wuerzburg, Germany

Our EFFORTs Moving Forward: Future Strategies to Enhance Signals from Critical Care Nutrition Trials 
Todd Rice, MD, MSc, Assistant Professor of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University, Nashville, TN

EASE SBS-1 Background and Results 
Palle Bekker Jeppesen, MD, PhD, Professor of Medicine; Head, Department of Intestinal Failure and Liver Diseases, Rigshospitalet, Copenhagen, Denmark

David Mercer, MD, PhD, FRCS (C), FACS, Professor of Surgery, Transplant, University of Nebraska Medical Center, Omaha, NE

Marion Winkler, PhD, RD, LDN, CNSC, Professor of Surgery, Alpert Medical School of Brown University; Surgical Nutrition Specialist, Rhode Island Hospital, Providence, RI

Manpreet Mundi, MD, Professor of Medicine, Department of Endocrinology, Mayo Clinic College of Medicine and Science, Rochester, MN