Differential Effects on Intestinal Adaptation Following Exogenous Glucagon-Like Peptide-2 Therapy With and Without Enteral Nutrition in Neonatal Short Bowel Syndrome

Release Date:  February 1, 2017

Expiration Date (all CE credit must be claimed by the expiration date):  February 28, 2018

Issue: 2

Volume: 41

Journal:  Journal of Parenteral and Enteral Nutrition (JPEN)

Author (s):

David W. Lim, MD, CM, Med, Physician, General Surgery Residency Program, Division of General Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

Abdoulaye Diané, PhD, Research Associate, Metabolic and Cardiovascular Disease Laboratory/Group on the Molecular and Cell Biology of Lipids/Alberta Diabetes Institute, University of Alberta, Edmonton, Canada

Mitsuru Muto, MD, PhD, Chief Physician/Surgeon, Department of Neonatology, Perinatal Medical Centre, Kagoshima City Hospital, Kagoshima, Japan

Donna F. Vine, PhD, Honorary Research Fellow, Dentistry and Health Sciences, Faculty of Medicine, University of Western Australia, Perth, WA; Associate Professor, Division of Human Nutrition, ALES/North Campus, University of Alberta, Edmonton, Alberta, Canada

Patrick N. Nation, PhD, President, Animal Pathology Services APS Ltd., Edmonton, Alberta, Canada

Pamela R. Wizzard, BSc, RAHT, Swine Research Technician - Surgical, Swine Research and Technology Center, Edmonton, Alberta, Canada

David L. Sigalet, MD, PhD, FRCSC, FACS, Vice Chair of Surgery, Weill Cornell Medical College, New York, NY; Professor of Surgery, Weill Cornell Medical College, Qatar, Doha, Qatar; Adjunct Professor of Surgery, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada

David L. Bigam, MD, MSc, FRCSC, Professor of Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

Paul B. Pencharz, MB, ChB, PhD, FRCPC, Professor of Pediatrics and Nutrition, University of Toronto, Toronto, Ontario, Canada

Justine M. Turner, MBBS, PhD, FRACP, Associate Professor, Division of Gastroenterology and Nutrition, University of Alberta, Alberta, Canada

Paul W. Wales, MD, MSc, FRCSC, FACS, Senior Associate Scientist, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada

Format: Online as PDF or hard copy of journal

Link to article: Link

Journal-based CE Activity Overall Goal:

The JPEN Editor, in concurrence with A.S.P.E.N.’s Education and Professional Development Committee, selected this article to be offered for CE credit to fill an observed learning need in the arena of clinical nutrition and metabolism.  This CE activity serves to promote the process of life-long learning for physicians, dietitians, pharmacists, and nurses by providing peer-reviewed journal articles that fully qualify for continuing education credits.

Goal and Target Audience:

This educational activity is directed toward clinical nutrition and metabolism professionals and others who wish to update their knowledge of clinical nutrition and metabolism. By participating in this educational activity, the reader may expect to:

• Acquire knowledge in the area of clinical nutrition and metabolism research
• Update or confirm your understanding of appropriate clinical nutrition and metabolism practices.
• Identify further learning needs as they relate to the subject matter.

Learning Objectives:

1. Describe the intestinal physiological response, known as adaptation, that is expected to follow a significant surgical resection of the small intestine
2. Describe the intestinal physiological response to glucagon like peptide-2 in the presence or absence of enteral nutrition
3. Describe how the intestinal physiological responses to glucagon like peptide-2 vary according to remnant small intestinal anatomy

Requirements for Successful Completion:
To obtain CE credit for this activity, attendees must read the journal article in its entirety, complete an online knowledge assessment for each article and achieve a score of 100%, and complete an online activity evaluation. All CE credit must be claimed prior to the expiration date.    

Accreditation Statements/Continuing Education Credit:

Nurses, Pharmacists and Physicians

In support of improving patient care, The American Society for Parenteral and Enteral Nutrition (ASPEN) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

This activity is for a maximum of 1 contact hour (0.1 CEU) per journal article and is a knowledge activity. 

A.S.P.E.N. designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credits ^TM per article. Physicians should only claim credit commensurate with the extent of their participation in the activity.

A.S.P.E.N. is approved by the California Board of Registered Nursing, Provider CEP 3970.

ACPE UAN: 0216-0000-17-054-H01-P. Knowledge activity. 

Dietitians

A.S.P.E.N., Provider Number AM005, is a Continuing Professional Education (CPE) Accredited Provider with the Commission on Dietetic Registration (CDR).   CDR level 2.  Dietitians may post comments on this program on www.cdrnet.org.

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No commercial support or sponsorship has been received for this continuing education activity.

Commercial Relationships Disclosures and Conflicts of Interest (COI) of Authors and Editor-in-Chief and Associate Editors

The following authors have nothing to disclose:  David Lim, Patrick Nation, Paul B. Pencharz, Donna F. Vine, Paul W. Wales, Justine M. Turner, Pamela R. Wizzard, Abdoulaye Diané, David L. Bigam, Mitsuru Muto  

David Sigalet has served as a consultant for Shire Pharma and received honorarium;

JPEN Associate Editors: David August, Ronald Koretz, Ding-You Li, Jean-Charles Preiser, and Diana Mager have nothing to disclose. Mark Puder has served on the Pronova advisory board and received grant funding and consulting fee.

JPEN Editor-in-Chief Kelly Tappenden has served in a speaking role for NPS Pharmaceuticals, Inc, Nutricia, and Abbott Nutrition. Has received honoraria for those roles.

No conflicts related to disclosure information present and subsequently no need for resolution. Standard journal peer-review process also in place as another layer of review to ensure no conflicts to resolve.